Risks of Combining Downer and Upper Drugs
“Downer” and “upper” drugs are casual terms that refer to how different substances act on the central nervous system (CNS). In short, downers are depressants and uppers are stimulants. Downers commonly include sedatives and tranquilizers, such as benzodiazepines and barbiturates. Uppers include drugs like amphetamine, methamphetamine, and cocaine. In addition to sedatives, many other substances […]
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